Vitamin D surfaces as a news topic every few months. How much daily
vitamin D should a person get? Is it possible to have too much of it?
Is exposure to the sun, which is the body's natural way of producing
vitamin D, the best option? Or do supplements suffice?.
In the July 2010 issue of Endocrine Today, a monthly newspaper
published by SLACK, Inc., to disseminate information about diabetes and
endocrine disorders, Anthony Norman, a distinguished professor emeritus
of biochemistry and biomedical sciences and an international expert on
vitamin D, notes that half the people in North America and Western
Europe get insufficient amounts of vitamin D.
"Elsewhere, it is worse," he says, "given that two-thirds of the people
are vitamin D-insufficient or deficient. It is clear that merely eating
vitamin D-rich foods is not adequate to solve the problem for most
adults." .
Currently, the recommended daily intake of vitamin D is 200
international units (IU) for people up to 50 years old; 400 IU for
people 51 to 70 years old; and 600 IU for people over 70 years old.
"There is a wide consensus among researchers that the relative daily
intake of vitamin D should be increased to 2,000 to 4,000 IU for most
adults," Norman says. "A 2000 IU daily intake can be achieved by a
combination of sunshine, food, supplements, and possibly even limited
tanning exposure".
While there is now abundant data on vitamin D and its benefits, Norman
believes there is room for more study.
"The benefits of more research on the topic justifies why this field of
research deserves additional governmental funding," he says. "Already,
several studies have reported substantial reductions in occurence rate
of breast cancer, colon cancer and type 1 diabetes in association with
adequate intake of vitamin D, the positive effect generally occurring
within five years of initiation of adequate vitamin D intake."
Because vitamin D is found in very few foods naturally (e.g. fish, eggs
and cod liver oil) other foods such as milk, orange juice, some yogurts
and some breakfast foods are fortified with it. The fortification levels
aim at about 400 IU per day.
Norman, who holds the title of Presidential Chair in
Biochemistry-Emeritus, has been researching vitamin D for nearly 50
years. In 1967, his laboratory discovered that the vitamin is converted
into a steroid hormone by the body. Two years later, his laboratory
discovered the vitamin D receptor (or VDR), an essential receptor for
the steroid hormone form of vitamin D that is present in more than 37
target organs of the body that respond biologically to the vitamin.
"There is now irrevocable evidence that receptors in the immune,
pancreas, heart-cardiovascular, muscle and brain systems in the body
generate biological responses to the steroid hormone form of vitamin D,"
he says.