MINNEAPOLIS – A study carried out at the University of Minnesota and the University of Colorado-Boulder has revealed successful treatment of a serious gut infection commonly referred to as Clostridium difficile by the simple use of fecal transplants.

The fecal transplantations that were otherwise of about are said to have a long-term healthy change impact to a patient’s microbiome which are sustained for up to 21 weeks after transplant.

Clostridium difficile to be treated using fecal transplants

Clostridium difficile infections are a growing by day thus becoming problematic to many households. The recurrent cases of diarrhea and severe abdominal pain accompanied by thousands of fatalities are as a result of Clostridium difficile infections. However, Fecal Microbiota transplantation which was developed as a method of treating C. difficile infection has given very successful results in the treatment of repeat infections.

Fecal matter is first collected from a donor then purified and mixed with a saline solution and eventually placed into a patient usually by colonoscopy. All this was done using fecal samples collected from four patients before and after fecal transplants. Three of them received transplants that contained “freshly prepared” microbiota while the remaining one received contained material that had been frozen previously.

The pre and post results indicated that patients who received the transplants displayed substantial microbiome changes which would put then within a healthy spectrum that would last for up to 21 weeks. Michael Sadowsky the study author however explained that at any one time of fecal transplantation, the changes could either be long term or short term.

While it’s generally true that human beings may have similarities in fecal microbiota, there are individuals who may have differences which will bring the aspect of uniqueness. However, the apparent gut functioning is not in any way affected.

The U.S. Food and Drug Administration is considering fecal transplants to be a drug. With this it has its best interests in place for purposes of standardization which is being considered to be equally important. This means the research is likely to have regulatory implications for fecal transplantations.

Leave a Reply

Your email address will not be published.