Consuming B12 and folic acid supplements for a prolonged period might not help in increasing your memory, retaining power and thinking skills, according to new research published in anonline issue of Neurology, medical journal of the American Academy of Neurology.

Research was conducted over the people with high blood levels of homocysteine and amino acid as high level of homocysteine is generally linked with Alzheimer and memory loss.

“Since homocysteine levels can be lowered with folic acid and vitamin B12 supplements, the hope has been that taking these vitamins could also reduce the risk of memory loss and Alzheimer’s disease,” said study author Rosalie Dhonukshe-Rutten, of Wageningen University.

Early observations were synchronous with the age-old belief that taking B12 and folic acid might increasing memory and thinking skills but the results of later randomized and less convincing, confronting the age-old belief.

For the research, scientists included 2919 volunteers with an average age of 74, having high blood levels of homocysteine, who took either a tablet with 400 μg of folic acid and 500 μg of vitamin B12 or a placebo every day for two years. Volunteers underwent through several memory and thinking skill tests at the beginning and end of the day. After the tests researchers found that the participants showed no significant improvements.

“While the homocysteine levels decreased by more in the group taking the B vitamins than in the group taking the placebo, unfortunately there was no difference between the two groups in the scores on the thinking and memory tests,” said Dhonukshe-Rutten.

Several other organisations supported the study including the Netherlands Organization for Health Research and Development, the Dutch Dairy Association, MCO Health, Netherlands Consortium Healthy Aging, Dutch Ministry of Economic Affairs, Agriculture and Innovation, Wageningen Univ., VU Univ. Medical Center and Erasmus Medical Center, all based in the Netherlands.

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